To attend, please ensure you are registered for the ASBMR annual meeting. 

Fibrodysplasia ossificans progressiva (FOP) is a disabling connective-tissue genetic disease characterized by congenital malformations of the great toes and progressive heterotopic endochondral ossification (HEO) and is the most catastrophic of HEO disorders in humans. Often misdiagnosed as cancer or fibrosis, this disease makes muscle tissue and ligaments harden and form into bone tissue that develops outside the normal skeleton. Normally noticed during early childhood, FOP generally begins with features associated to the neck and shoulders, gradually working its way down the body and the limbs.

Join us as we discuss the consequences of a delayed diagnosis with strategies for a proper evaluation to avoid misdiagnosis. Identification of episodic event triggers, management strategies, and discussion of current studies including an update on the first oral treatment available will be addressed.

Presenters

Accreditation

EXCEL Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

EXCEL Continuing Education designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Canadian CME: Through an agreement between the ACCME and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

The UEMS-EACCME®: The American Medical Association (AMA) has an agreement of mutual recognition of CME credit with the UEMS. Under the terms of this agreement, the European Accreditation Council for Continuing Medical Education (EACCME), the accrediting arm of the UEMS, will convert CME credit for live and enduring activities certified by the AMA.

Physician Assistants and Nurse Practitioners: The National Commission on Certification of Physician Assistants (NCCPA) and the American Academy of Nurse Practitioners (AANP) accept AMA PRA Category 1 Credit™ from organizations accredited by ACCME through its reciprocity agreements.

Educational Objectives

At the conclusion of this conference, you should be able to:

• Identify the causes, signs, and symptoms associated with FOP
• Develop a work-up procedure to arrive at a diagnosis of FOP that incorporates genetic testing, clinical evidence, and imaging diagnostics
• Explain the national history of episodic flare-ups that lead to disabling heterotopic ossification (HO)
• Develop an integrative management plan involving medication, trauma avoidance, and supportive care principles
• Review clinical trial data regarding the role of reducing new abnormal bone formation for FOP-specific therapies

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